Separate sources
LIMS, QMS, QC software, equipment logs, lot records, EQA portals and rosters each hold part of the truth.
About Xaloreli
Continuous proof that existing systems agree.
Xaloreli is being developed as a vendor-neutral evidence-assurance layer for pathology laboratories. It reconstructs the chain behind sampled reported results and checks whether the independently maintained records describe the same compliant reality.
Vendor-neutralWorks across separate source systems
Read-only firstDoes not alter clinical records
Human-governedQuality judgement remains in control
Result-levelAssures the full evidence thread
Where the idea comes from
Grounded in the reality of laboratory work
The Xaloreli concept grew from frontline NHS laboratory work involving sample preparation, basic testing, quality-control activity, equipment operation, reagent handling and LIMS recording. It made a practical problem visible: strong systems of record can coexist while the links between them remain untested.
The concept is also informed by previous work in quality assurance, SOP and training documentation, and nonconformance management, supported by operations, project-management and product training. Product development is intended to include a technical lead, an appropriately registered biomedical scientist or quality adviser, and specialist security and information-governance input.
The problem
The evidence behind one result is distributed across independent systems.
A vertical audit may need to prove who performed and authorised the test, whether competency was current, whether IQC had passed, which lots were in use, whether the instrument was available, which SOP applied and whether EQA performance was acceptable.
Hidden contradictions
Each system can be internally correct while disagreeing with another about the same result.
Manual vertical audits
Expert teams trace only a small sample of results because end-to-end reconstruction takes time.
Time-sensitive competence
Current competency at review does not prove authorisation was current when the work occurred.
Multi-site complexity
Networks combine different LIMS instances, analyser fleets, staff pools and local practices.
Late findings
Evidence breaks can remain invisible until audit preparation or external assessment.
The Xaloreli approach
Thread-Level Evidence Reconciliation
The proposed methodology changes the unit of assurance from an isolated record to the reported result and the complete evidence thread that should support it.
Anchor and resolve
Take a reported result as the anchor and resolve the person, instrument, QC run, lots, SOP, EQA position and roster state that applied at that time.
Reconcile
Test linked records with transparent rules that describe how independently maintained sources should agree.
Weight
Increase sampling for critical tests, new lots, post-maintenance work, temporary staff and areas with recent break history.
Evidence and close
Fingerprint source snapshots, confirm findings and return approved nonconformances to the laboratory's existing QMS.
How it fits
Complementary to established laboratory systems
Xaloreli is not another LIMS, QMS or POCT middleware product. It reads their records, tests consistency across them and uses the laboratory's QMS as the destination for confirmed findings.
Independent records
LIMS activity, QMS competency and documents, IQC, EQA, lots, equipment, roster and POCT middleware.
Build and reconcile
Risk-weighted sampling, time-bounded evidence threads, cross-system rules and source fingerprints.
Act in existing workflows
Confirmed QMS findings, network assurance metrics and scoped Thread Packs for internal or authorised review.
Who it is for
Different responsibilities, one evidence environment
Laboratory quality managers
Review overnight breaks, confirm findings and open Thread Packs for internal audit and assessment preparation.
Section leads and senior BMS staff
Investigate discipline-specific evidence breaks inside the existing QMS.
Network quality leads
Compare thread coverage, break rates and closure times across sites and disciplines.
Bench staff
Continue using familiar systems with no additional routine data entry.
Independent laboratory quality leads
Demonstrate continuous evidence-backed assurance for customers and tenders.
Authorised assessors
Review selected, clause-mapped Thread Packs through scoped and expiring access.
Why the approach is different
The unit of assurance is the reported result.
QMS, LIMS and middleware products create and manage evidence within their own records. Manual vertical audits check across systems, but only periodically. Xaloreli is designed to combine cross-system checking with continuous, risk-weighted automation.
Sampled by risk
New lots, post-maintenance activity, temporary staff and recent EQA concerns receive greater coverage.
Competency at task
The check uses the exact time of testing or authorisation, not only the status visible at the next audit.
Neutral by design
Value increases when a laboratory has multiple vendors because Xaloreli is not trying to replace them.
Reproducible findings
Source-snapshot fingerprints allow the laboratory to show what each system stated when the rule ran.
Rule sandbox
Quality leads can trial a rule against historical data and tune false positives before activation.
Network learning
Coverage, break rates and closure times highlight where evidence practices differ between sites.
Product principles
Trust depends on what the platform refuses to hide.
The product is intended to support professional judgement, not replace it.
- Verify rather than replace.Increase the value of systems laboratories already use.
- Show both sources.Make every contradiction and rule visible to the reviewer.
- Read clinical systems only.Keep write access away from the sample-to-result pathway.
- Confirm before write-back.Let quality managers dismiss false positives before creating a QMS finding.
- Minimise data.Use operational metadata and pseudonymise sample references where possible.
Development approach
File-first pilots before network-scale integration
Xaloreli is at concept-demonstration stage. The proposed route validates source availability, rule accuracy, false-positive control and measurable value before broader deployment.
Define the first rule families
Interview quality and network leads, confirm realistic exports and select high-value cross-system checks.
One discipline for 12 weeks
Run historical and scheduled file extracts, measure breaks found and compare effort with manual vertical audit.
Add connectors, sites and disciplines
Develop supported vendor integrations, network reporting, POCT sources and procurement readiness after pilot proof.
Clear boundaries
What Xaloreli is not
- It is not a LIMS, QMS or POCT middleware platform.
- It does not interpret, alter or release patient results.
- It does not grant or guarantee accreditation.
- It does not replace qualified laboratory, clinical or quality judgement.
- It does not score individual staff performance.
Explore how the evidence model works across the service.
The demonstration uses fictional records to show the intended workflows, roles and assurance outputs.